SILK CLINICTOKYO SILK CLINIC
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EXOSOMES

Exosomes

Signalling factors collected from stem cell culture are delivered into the skin or the bloodstream. The intent is to prompt cells whose activity has declined with age. This is among the most requested treatments by patients travelling to Japan and Korea, and also among the newest — long-term data is not yet established.

Time
20–60 min
Downtime
1–2 days
Sessions
3–5
From
$170

Who it suits

  • Firmness and elasticity have declined
  • You want to raise overall skin quality
  • Other treatments have not been enough
  • You want a regenerative approach with little downtime
  • You would like a whole-body option as well as facial

PackagesALL-INCLUSIVE

Each package covers the consultation with the doctor, the treatment named in that package, topical anaesthetic where it is used, and aftercare guidance. Nothing is added to the price of the package itself. If you decide during the consultation to add a further treatment, an additional area, or a stronger anaesthetic, that is charged separately — the doctor will tell you the amount before anything is carried out.

Exosome Facial1cc, injected by doctor
$420¥67,000
Exosome Facial — Intensive3cc, injected by doctor
$1,020¥163,000
Exosome IV DripWhole-body administration
$690¥110,500
Exosome with Dermapen1cc delivered by micro-needling
$170¥27,000
ABOUT PRICING

Prices are shown in US dollars. Payment is taken in Japanese yen at the equivalent amount shown, by cash or credit card. The conversion is fixed at ¥160 to the dollar and is reviewed quarterly, so it will not track the daily exchange rate.

About additional charges. The package price covers the treatment you select. Adding another treatment, another area, or an option such as nitrous oxide sedation or a blunt cannula is charged on top. The doctor explains the cost before proceeding, and you are free to decline.

LANGUAGE

How we communicate. Consultations are usually conducted with the help of a translation app, which our staff use routinely and which works well for the questions that come up in a consultation. Some of our doctors and staff can also handle straightforward English. Please write down anything you particularly want to ask before your visit — it makes the consultation smoother, and you are welcome to send questions on LINE in advance.

What happens

  1. Book

    Reserve online or on LINE.

  2. Consultation

    We decide the delivery method and volume.

  3. Anaesthetic

    Topical cream for injection; none needed for IV.

  4. Treatment

    About 20 minutes for injection, an hour for IV.

  5. Go home

    Redness may occur. Make-up depends on the method used.

  6. Course

    Monthly, three to five times.

Risks and side effects

Redness, swelling and bruising at the injection site can occur. Allergic reaction is possible. With intravenous administration, vein discomfort or feeling unwell can occur.

Who cannot be treated

Not suitable during pregnancy or breastfeeding, with a current or previous malignancy, or with infection at the treatment site.

Please note

Results vary between individuals and no particular outcome can be guaranteed. This is elective private treatment and is not covered by Japanese national health insurance.

The device, product or needle used is selected by the doctor based on your skin condition, your goals and your condition on the day. For detailed questions, asking the doctor directly at your consultation is the most reliable way. You may also ask on LINE, but technical questions need to be checked with our clinical staff first, so a reply may take some time.

Approval status
Not approved under Japan's Pharmaceuticals and Medical Devices Act.
How obtained
Imported personally by the doctor under that Act.
Approved equivalents
No domestically approved product with the same indication exists.
Overseas information
Used cosmetically in several countries, but sufficient clinical data on long-term efficacy and safety has not yet been established.

Questions

Is the safety established?
Not fully. This treatment is not approved in Japan and long-term data is limited. We ask that you proceed only with this understood.
Injection or IV?
Injection for facial change; IV if you want a whole-body approach. Some patients have both.
When will I notice something?
Skin condition often feels different within days; firmness and texture change over weeks.
Can it be combined?
Commonly with dermapen or water shine. HIFU on the same day is also possible.
How many sessions?
Three to five, monthly. One session produces a change but it accumulates.
Does it hurt?
Topical anaesthetic is used for injection. IV involves only the needle insertion.

Also consider

RESERVE
Start with a consultation

Book online or message us on LINE. Consultation is free when you proceed with a treatment or prescription; otherwise a fee of ¥5,500 applies.